Non-Stationary External Energy Mechanisms in Cancer Diagnostics and Treatment

We explore the transformative potential of external energy in diagnosing and treating cancers at their core. The goal is to replace often harmful substances (like drugs) in patients with on-demand diagnostic and therapeutic events at the cellular level:
- By combining physics, nanotechnology, and biology, laser pulses are transformed into tiny explosions called plasmonic nanobubbles within cells
- By leveraging disease to create energy-converting structures, plasmonic nanobubbles deliver precise, effective, and rapid diagnostic and therapeutic effects that enhance traditional medicine
Real-time quantitative nature of plasmonic nanobubbles aligns with robotics and artificial intelligence to create cell-level medicine of the future. For example, plasmonic nanobubbles can instantly and safely detect and destroy aggressive cancer cells that are otherwise undetectable. We aim to bring this concept into clinical practice, integrating it into cancer diagnostics, biopsy, endoscopy, microsurgery, drug and gene delivery, and combination therapies.

Dmitri Lapotko obtained his MS in thermal physics, Ph.D. in laser defense applications from Belarus State University, and Doctor of Science in bioengineering from A.V. Lykov Heat and Mass Transfer Institute. His research in biophotonics and nanotechnology resulted in the invention of laser-generated plasmonic nanobubbles as a novel platform for diagnostic, therapeutic and surgical technologies for cancer and other diseases. Lapotko’s work, recently summarized in his book “Plasmonic Nanobubbles: From Physics to Clinics,” laid the foundation for non-stationary plasmonics and nanophotonics.