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Keynote Presentation (In-Person)
Title: Anti-cancer nanomedicine in humans: A review and future directions
This presentation will cover a close to 30 year journey researching and commercializing nanotechnology for improving disease prevention, diagnosis, and treatment (including cancer) which has led to numerous products including nano spinal implants now in over 30,000 patients to da [....] » Read More
Keynote Presentation (In-Person)
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized and precision medicine (PPM). Meanwhile, the era of genomics-based medicine and thus genomics biomarkers promises to provide molecular tests that will pe [....] » Read More
Oral Presentation (In-Person)
A comprehensive molecular tumor analysis integrating a combination of NGS methods including whole-exome (WES), whole-genome (WGS) and transcriptome sequencing (RNAseq) offers the best chance for personalizing cancer care, enlarging the scope of therapy choices and offering potent [....] » Read More
Oral Presentation (In-Person)
Title: Iodine and Caesium-137: Angels and Demons of evolutionary Biology, in Pancreatic Cancer and Diabetes
The Chernobyl nuclear accident, on 1986, marked a turning point in both the history of energy production and our understanding of the relationship between human technology and life. J.R. Oppenheimer evoked the famous Hindu scripture, “Now I am become Death, the&nb [....] » Read More
Oral Presentation (In-Person)
Background: The clinical management of gynecologic malignancies—endometrial (EC), ovarian (OC), and cervical (CC) carcinomas—has been historically guided by histomorphology and staging. This paradigm fails to capture profound molecular heterogeneity, resulting in [....] » Read More
Oral Presentation (In-Person)
Background and Purpose: Chaperone-mediated autophagy (CMA) is a selective degradation pathway that is highly active in various malignancies, including non-small cell lung cancer (NSCLC), and contributes to tumor progression. Currently, no targeted chemical inhibitors of CMA [....] » Read More
Poster Presentation (In-Person)
Introduction: The tumor immune microenvironment (TIME) of KRAS-mutant lung adenocarcinoma (LUAD) is predominantly characterized by an immunosuppressive phenotype, which underpins its resistance to immunotherapy. This study aims to elucidate the role and molecular mechanism o [....] » Read More
Poster Presentation (In-Person)
Background: Mast cell sarcoma is an exceptionally rare and highly aggressive neoplasm characterized by a localized, destructive proliferation of atypical mast cells, most frequently involving bone. It may progress to mast cell leukemia (MCL), a systemic and often rapidly fatal di [....] » Read More
Poster Presentation (In-Person)
Background: Myeloid neoplasms with germline predisposition comprise a heterogeneous group of disorders caused by deleterious inherited variants in genes conferring susceptibility to hematologic malignancies¹. Germline variants in DDX41, located on chromosome 5 and inher [....] » Read More
Keynote Presentation (Virtual)
Title: Prospecting fluorine-doped graphene in photodynamic therapy
Halogen-decorated graphene quantum dots (X@GQDs) will be herein explored as a material platform for application in photodynamic therapy (PDT). GQDs have been extensively studied in biomedical areas such as bioimaging, bio-sensing and photothermal therapy due to their superior opt [....] » Read More
Oral Presentation (Virtual)
During the last decade there have been major breakthroughs in cancer treatment options driven by immunotherapy and most recently cell and gene products. With increased number of new cancer drug candidates entering clinical development there is elevated need for identification of [....] » Read More
Oral Presentation (Virtual)
Title: A new Universal Fever Definition and the unscientific nature of the conservative fever definition.
No medical textbook tells us what the purpose of fever is. Without knowing this, no one in the world can define, test, or treat fever. The current definition, testing, and treatment of fever, which is constructed without knowing what the purpose of fever is, has no scientific bas [....] » Read More
Oral Presentation (Virtual)
Background: Intracerebral hemorrhage (ICH) triggers a profound neuroinflammatory cascade in which microglial polarization critically influences secondary brain injury and neurological outcomes. Clinical data revealed that Hspd1 expression is significantly elevated in circulating [....] » Read More
Oral Presentation (Virtual)
Pulmonary surfactant proteins (SP-A, SP-B, SP-C, and SP-D) are essential regulators of alveolar surface tension and pulmonary immune defense, constituting a critical frontline barrier against airborne xenobiotics. Increasing environmental pollution exposes the respiratory system [....] » Read More
Poster Presentation (Virtual)
Background: Patients with acute leukemia who experience neutropenia after intensive chemotherapy have a high risk of developing Invasive Fungal Infections (IFIs), which can be life threatening. Although diagnostics and supportive care have been enhanced, IFIs continue to be a maj [....] » Read More
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