Refine the list (min. 2 characters)
Keynote Presentation (In-Person)
Title: Anti-cancer nanomedicine in humans: A review and future directions
This presentation will cover a close to 30 year journey researching and commercializing nanotechnology for improving disease prevention, diagnosis, and treatment (including cancer) which has led to numerous products including nano spinal implants now in over 30,000 patients to da [....] » Read More
Keynote Presentation (In-Person)
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized and precision medicine (PPM). Meanwhile, the era of genomics-based medicine and thus genomics biomarkers promises to provide molecular tests that will pe [....] » Read More
Keynote Presentation (In-Person)
Title: Precise deep detection of tumoral biomarkers using large-scale confocal x-ray fluorescence
Precise detection of tumor targets located at clinically relevant depths remains a major challenge in oncologic imaging. In this work, a large-scale confocal X-ray fluorescence (XRF) system was evaluated for deep detection of high-Z biomarkers embedded in tissue-equivalent media. [....] » Read More
Oral Presentation (In-Person)
Title: Iodine and Caesium-137: Angels and Demons of evolutionary Biology, in Pancreatic Cancer and Diabetes
The Chernobyl nuclear accident, on 1986, marked a turning point in both the history of energy production and our understanding of the relationship between human technology and life. J.R. Oppenheimer evoked the famous Hindu scripture, “Now I am become Death, the&nb [....] » Read More
Oral Presentation (In-Person)
A comprehensive molecular tumor analysis integrating a combination of NGS methods including whole-exome (WES), whole-genome (WGS) and transcriptome sequencing (RNAseq) offers the best chance for personalizing cancer care, enlarging the scope of therapy choices and offering potent [....] » Read More
Oral Presentation (In-Person)
Background: The clinical management of gynecologic malignancies—endometrial (EC), ovarian (OC), and cervical (CC) carcinomas—has been historically guided by histomorphology and staging. This paradigm fails to capture profound molecular heterogeneity, resulting in [....] » Read More
Oral Presentation (In-Person)
Background and Purpose: Chaperone-mediated autophagy (CMA) is a selective degradation pathway that is highly active in various malignancies, including non-small cell lung cancer (NSCLC), and contributes to tumor progression. Currently, no targeted chemical inhibitors of CMA [....] » Read More
Poster Presentation (In-Person)
Introduction: Sacrococcygeal teratoma (SCT) is commonly observed in neonates but is extremely uncommon in adults, with an estimated incidence of 1 in 40,000–63,000 and a marked female predominance(1,2,8). In adults, SCTs are generally intrapelvic (Altman Types III/IV), exhi [....] » Read More
Poster Presentation (In-Person)
Introduction and Importance: Multiple primary malignant neoplasms (MPMNs) are defined as two or more histologically distinct malignancies occurring in a single patient. Synchronous tumors are rare and present a diagnostic challenge, particularly in distinguishing metastatic disea [....] » Read More
Poster Presentation (In-Person)
Title: Clinicopathological characteristics and prognosis of mucinous breast carcinoma
Background: Mucinous breast carcinoma (MuBC) is a rare special type of breast cancer, which can be classified into pure mucinous breast carcinoma (PMuBC) and mixed mucinous breast carcinoma (MMuBC) types based on the proportion of mucinous components. This study aims to compare t [....] » Read More
Poster Presentation (In-Person)
Esophageal squamous cell carcinoma (ESCC) metastasis remains a major cause of poor prognosis. Acetyl?CoA carboxylase 1 (ACC1), a rate?limiting enzyme in fatty acid synthesis, has been implicated in tumor progression but its role in ESCC is unclear. This study investigated whether [....] » Read More
Poster Presentation (In-Person)
Introduction: The tumor immune microenvironment (TIME) of KRAS-mutant lung adenocarcinoma (LUAD) is predominantly characterized by an immunosuppressive phenotype, which underpins its resistance to immunotherapy. This study aims to elucidate the role and molecular mechanism o [....] » Read More
Keynote Presentation (Virtual)
Title: Prospecting fluorine-doped graphene in photodynamic therapy
Halogen-decorated graphene quantum dots (X@GQDs) will be herein explored as a material platform for application in photodynamic therapy (PDT). GQDs have been extensively studied in biomedical areas such as bioimaging, bio-sensing and photothermal therapy due to their superior opt [....] » Read More
Keynote Presentation (Virtual)
Title: Multiplexed sensor-based detection of biomarkers for early-stage ovarian cancer
In the present paper we discuss the application of biosensor technology for the early-stage detection of ovarian cancer.Several biomarkers have been identified for OC, of which cancer antigen-125 (CA125) is the only one currently clinically approved. In our research, we are worki [....] » Read More
Keynote Presentation (Virtual)
Title: Non-Stationary External Energy Mechanisms in Cancer Diagnostics and Treatment
We explore the transformative potential of external energy in diagnosing and treating cancers at their core. The goal is to replace often harmful substances (like drugs) in patients with on-demand diagnostic and therapeutic events at the cellular level: - By combining physics, n [....] » Read More
Keynote Presentation (Virtual)
Title: Precision oncology and blood-based mRNA genomics technology for cancer diagnosis and treatment
Current screening methods—radiological imaging, DNA-based tests, and pathological assessments—often fail to detect malignancies at early stages. Despite technological advances, gene-based diagnostics specifically designed for early cancer detection remain limited. To [....] » Read More
Oral Presentation (In-Person)
During the last decade there have been major breakthroughs in cancer treatment options driven by immunotherapy and most recently cell and gene products. With increased number of new cancer drug candidates entering clinical development there is elevated need for identification of [....] » Read More
Oral Presentation (Virtual)
Title: The small GTPase RhoA regulates the endothelial barrier during metastasis
The endothelial barrier plays an active role in transendothelial tumor cell migration during metastasis, however, the endothelial regulatory elements of this step remain obscure. Here we show that endothelial RhoA activation is a determining factor during this process. Breast tum [....] » Read More
Oral Presentation (Virtual)
Background: The structural complexity of antibody-drug conjugates (ADCs) poses unique pharmacokinetic and pharmacodynamic (PK/PD) challenges. A key hurdle lies in modeling the divergent elimination pathways of antibody and payload moieties, which substantially determine the [....] » Read More
Oral Presentation (Virtual)
Title: Decoding intestinal crypt morphogenesis: From tissue mechanics to tumor initiation
Intestinal cancers are among the most prevalent epithelial malignancies and constitute a major clinical burden, largely due to late diagnosis and difficulty of predicting disease progression. Tumorigenesis mainly initiates within intestinal crypts, which harbor stem cell (SC) and [....] » Read More
Oral Presentation (Virtual)
Title: Real world cancer pain incidence and treatment in daily hospital
Background: Approximately 34-67 percent of cancer patients experience an episode of uncontrolled pain during the course of their disease, depending on the stage. Aims: to provide real world data for pain prevalence, diagnosis and treatment recommendations on integrative model [....] » Read More
Oral Presentation (Virtual)
Purpose: This study evaluates the dosimetric advantages of Non-Coplanar Volumetric Modulated Arc Therapy (ncVMAT) over Coplanar Volumetric Modulated Arc Therapy (cVMAT) enabled by a novel O-ring gantry that permits couch rotation for Brain Tumours. Methods: Fifteen p [....] » Read More
Oral Presentation (Virtual)
Introduction: Obesity has been recently shown to affect serum tumor markers, potentially influencing the sensitivity of screening programs and interpretation of results. Expansion of plasma volume and chronic inflammation may drive these differences, which may affect markers disp [....] » Read More
Oral Presentation (Virtual)
Title: A new Universal Fever Definition and the unscientific nature of the conservative fever definition.
No medical textbook tells us what the purpose of fever is. Without knowing this, no one in the world can define, test, or treat fever. The current definition, testing, and treatment of fever, which is constructed without knowing what the purpose of fever is, has no scientific bas [....] » Read More
Oral Presentation (Virtual)
Background: Intracerebral hemorrhage (ICH) triggers a profound neuroinflammatory cascade in which microglial polarization critically influences secondary brain injury and neurological outcomes. Clinical data revealed that Hspd1 expression is significantly elevated in circulating [....] » Read More
Oral Presentation (Virtual)
Title: Assessing Human Exposure to Key Chemical Carcinogens Diagnostic Approaches and Interpretation
Chemical carcinogens classified by the International Agency for Research on Cancer (IARC) as Group 1 very probably contribute to cancer occurrence in over 13.5 million people and death from cancer in over seven million people. In percent, chemical elements and chemical compounds [....] » Read More
Oral Presentation (Virtual)
Title: RNA theranostics in cancer
RNA theranostics is emerging as a transformative approach in oncology, offering powerful opportunities for both cancer diagnosis and precision treatment. Recent advances in nanomedicine and biomaterials have enabled the design of sophisticated RNA-based platforms, including mRNA, [....] » Read More
Oral Presentation (Virtual)
Title: Radosavljevic urinary screening biomarkers of the key chemical carcinogens for bladder cancer
The aim of the study was to examine the possibility of using the urinary concentration of 1-hydroxypyrene for screening high-risk male individuals for bladder cancer. Radosavljevi?′s urinary screening protocol for the key chemical carcinogens used. Numerical data were arith [....] » Read More
Oral Presentation (Virtual)
Pulmonary surfactant proteins (SP-A, SP-B, SP-C, and SP-D) are essential regulators of alveolar surface tension and pulmonary immune defense, constituting a critical frontline barrier against airborne xenobiotics. Increasing environmental pollution exposes the respiratory system [....] » Read More
Oral Presentation (Virtual)
Treatment of cancer with heavy ions, like proton and carbon ions, has its challenges based on precision for dose calculation. One of the major contributors to this precision in the case of proton therapy is proton range which is calculated using proton stopping power ratio. This [....] » Read More
Poster Presentation (Virtual)
This study establishes a validated prognostic model based on NK cell-associated long noncoding RNAs (lncRNAs) to predict outcomes in colorectal cancer (CRC), a malignancy characterized by poor prognosis and limited response to conventional therapies. By integrating single-cell RN [....] » Read More
Poster Presentation (Virtual)
The purpose of this investigation was to develop and validate a risk model based on natural killer (NK) cell-associated lncRNAs to predict outcomes in individuals with hepatocellular carcinoma (HCC). To further explore the role of NK cells in the HCC tumor microenvironment, we le [....] » Read More
Poster Presentation (Virtual)
Background: Patients with acute leukemia who experience neutropenia after intensive chemotherapy have a high risk of developing Invasive Fungal Infections (IFIs), which can be life threatening. Although diagnostics and supportive care have been enhanced, IFIs continue to be a maj [....] » Read More
Copyright 2024 Mathews International LLC All Rights Reserved
