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Keynote Presentation (In-Person)
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized and precision medicine (PPM). Meanwhile, the era of genomics-based medicine and thus genomics biomarkers promises to provide molecular tests that will pe [....] » Read More
Keynote Presentation (In-Person)
Pancreatic cancer (PC) is difficult to treat and has the lowest five-year survival rate across the world. PC is characterized by desmoplasia composed of abundant cancer-associated fibroblasts (CAFs) and excessive extracellular matrix (ECM), which creates a pathological barrier th [....] » Read More
Keynote Presentation (In-Person)
Title: Anti-Cancer nanomedicine in humans: 30,000 successful cases and counting
This presentation will cover a close to 30 year journey researching and commercializing nanotechnology for improving disease prevention, diagnosis, and treatment (including cancer) which has led to numerous products including nano spinal implants now in over 30,000 patients to da [....] » Read More
Keynote Presentation (In-Person)
Title: Intelligent oncology: The transformative role of AI in the future of cancer research and care
Artificial Intelligence (AI) is poised to revolutionize oncology by transforming how we detect, understand, and treat cancer. As cancer remains a leading cause of death globally, integrating AI into research and clinical workflows offers unprecedented opportunities to address its [....] » Read More
Keynote Presentation (In-Person)
Recreating the complexity of the tumor microenvironment is essential for advancing cancer research. Three-dimensional (3D) biomaterials offer a powerful platform for replicating the biological, chemical, and mechanical properties of native tissues, providing a more physiologicall [....] » Read More
Oral Presentation (In-Person)
Title: Copper(II) complexes as potent chemotherapeutic agents for anticancer therapy
Cancer is the second top leading cause of death worldwide. According to WHO, approximately 10 million individuals died of cancer in 2022, and this number is expected to rise to 16.4 million by 2040. Since the FDA approval of cisplatin as a chemotherapeutic drug for cancer treatme [....] » Read More
Oral Presentation (In-Person)
Title: Suppression of breast cancer by small molecules that block the prolactin receptor
Background: Prolactin (PRL) is a protein hormone whose main production site is the pituitary gland. In humans, however, PRL is produced and secreted not only by the pituitary but also by other cells such as adipocytes, lymphocytes and mammary cells. The PRL receptor (PRLR) belong [....] » Read More
Oral Presentation (In-Person)
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized and precision medicine (PPM). The concept of PPM is becoming increasingly relevant for cancer treatment, moving from the ‘one-size-fits-all’ [....] » Read More
Oral Presentation (In-Person)
Title: Artificial intelligence (AI) and the examination of the cornea at the slit lamp
The slit lamp is an obligatory instrument for every ophthalmologist. It was invented by Alvar Gullstrand in 1910. Over the following decades, the slit lamp has been supplemented by additional applications such as the three-mirror contact lens and the magnifying glass, the applana [....] » Read More
Oral Presentation (In-Person)
Title: Lactate dehydrogenase B noncanonically promotes ferroptosis defense in KRAS-driven lung cancer
Ferroptosis is an oxidative, non-apoptotic form of cell death that is frequently inactivated in cancer, yet its regulation in oncogene-specific tumors remains poorly understood. Here, we identify lactate dehydrogenase B (LDHB)—but not the closely related LDHA—as a non [....] » Read More
Oral Presentation (In-Person)
Background. The role of systemic inflammation in carcinogenesis has been studied for a long time. Markers of systematic inflammation response, such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR), are associated with the u [....] » Read More
Oral Presentation (In-Person)
Title: Lytic bone lesion of the skull a rare manifestation of hepatocellular carcinoma: A case report
Background: Hepatocellular carcinoma (HCC) ranks among the leading causes of cancer-related deaths worldwide, with metastatic spread to bones being alarmingly frequent. However, HCC metastases to the skull are notably rare, accounting for only 0.4-1.6% of all bone metastases [....] » Read More
Oral Presentation (In-Person)
Title: Targeting glioblastoma multiforme through a multifaceted therapeutic drug approach
Being the most aggressive primary brain tumor in adults Glioblastoma multiforme (GBM) represents a formidable challenge for clinicians. Despite multifaceted treatment strategy encompassing surgical intervention, radiation therapy, and chemotherapy, the prognosis for GBM patients [....] » Read More
Oral Presentation (In-Person)
Title: Prognosis factors of rectal cancer
The local control rate of rectal cancer has increased with multimodal treatment consisting of chemotherapy, surgery, and radiation therapy; however, overall survival and the risk of metastatic relapses have remained unchanged. Our study's objective was to examine the prognost [....] » Read More
Oral Presentation (In-Person)
Aim: Contouring in treatment planning systems for radiation oncology plays a crucial role in ensuring accurate and effective treatment. The integration of AI-generated auto-contouring with other planning systems, particularly in remote areas, is essential for achieving optimal co [....] » Read More
Oral Presentation (In-Person)
Title: Tumor-specific mutation induced cytoplasm-localized ARID1B regulates RNA metabolism
AT-rich interaction domain 1B (ARID1B), a mammalian SWI/SNF (also termed BAF) chromatin remodeling complex component, is frequently inactivated in several cancer types. Previous studies from our laboratory have revealed a possible cytoplasmic oncogenic gain-of-function of mutant [....] » Read More
Oral Presentation (In-Person)
Background and aims: Cancer is a group of diseases characterized by abnormal cell growth and proliferation. These cancerous cells can destroy other healthy cells in the body and have the ability to replicate and spread from one organ to another within the human body. Cancer is th [....] » Read More
Oral Presentation (In-Person)
Title: HER2/neu – A prognostic marker for ovarian carcinoma
Ovarian carcinoma is the 2nd most common gyneacological malignancy and has a poor 5 year survival rate despite available therapies. This study was conducted to evaluate the association of HER2/neu with the clinicopathological features of epithelial ovarian carcinoma. 90 patients [....] » Read More
Oral Presentation (In-Person)
Title: Key mechanisms driving extravillous trophoblast lineage imbalance in placenta accreta spectrum
Background: Placenta Accreta Spectrum (PAS) represents a serious pregnancy complication characterized by abnormal invasion of extravillous trophoblasts (EVTs) into the uterine myometrium, leading to high risks of maternal morbidity and mortality. Although EVTs play a c [....] » Read More
Oral Presentation (In-Person)
Title: Preclinical study on new parathyroid recognition technology in thyroid surgery
Background: The parathyroid gland is the smallest organ in the organism, with an important function of regulating blood calcium in the human body. The accidental resection of the parathyroid gland during thyroid surgery cannot be ignored, so attention should be paid to the identi [....] » Read More
Oral Presentation (In-Person)
NETosis and ETosis are processes involving the release of extracellular traps (ETs). They have been linked to cancer progression, particularly in promoting metastasis and tumor-associated thrombosis. This indicates that redundant NETs/ETs formation can contribute to cancer spread [....] » Read More
Oral Presentation (In-Person)
Title: The role of oral habits in the incidence of oral and jaw cancers and their surgical treatment
Oral and jaw cancers, particularly oral squamous cell carcinoma (OSCC), constitute a significant clinical challenge within the field of maxillofacial surgery. In recent decades, the role of deleterious oral habits as independent or synergistic etiological factors has been incre [....] » Read More
Oral Presentation (In-Person)
Introduction: Paclitaxel is one of the most widely used chemotherapy drugs in the treatment of breast cancer. NK cell activation plays an important role in targeting tumor cells. Objectives: In this study, we aimed to find doses of paclitaxel that, despite [....] » Read More
Oral Presentation (In-Person)
Title: Investigation of risk factors for colorectal cancer
Colorectal cancer is the second leading cause of morality worldwide, representing a significant indicator for evaluating global cancer patterns and trends.[1, 2] Colorectal cancer is also the third most common malignancy worldwide, ranking third among men and second among women [....] » Read More
Oral Presentation (In-Person)
Title: Clinical significance of serum miR-21, CA153 and CEA in breast cancer
Objective: one of the essential regulators of carcinogenesis is MicroRNA-21 (miR- 21). Yet little light has been shed on its effectiveness as a tumor marker compared to the conventional ones. Comparing the diagnostic value of established tumor markers in breast cancer (BC) such a [....] » Read More
Poster Presentation (In-Person)
Background: Follicular variant of papillary thyroid carcinoma (FVPTC) is a histologic subtype of papillary thyroid carcinoma (PTC) characterized by follicular architecture with the nuclear features of classical PTC. FVPTC is considered more aggressive than conventional PTC, of [....] » Read More
Poster Presentation (In-Person)
Background Currently, immunotherapy through Adoptive Cell Transfer (ACT) of immune cells, such as T cells or Natural killer cells (NK cell), is being proposed as a new treatment in the treatment of various cancers. NK cell-based therapeutic research has been conducted mainly in [....] » Read More
Poster Presentation (In-Person)
Cancer remains the second leading cause of mortality worldwide, largely due to limitations of current therapies such as drug resistance, metastasis, and poor pharmacokinetic profiles. In search of more effective alternatives, Isoindole-1 3-dione a well-established anticancer scaf [....] » Read More
Poster Presentation (In-Person)
Background: Checkpoint inhibitor pneumonitis (CIP) and radiation pneumonitis (RP) lead to anti-cancer therapy discontinuation and poor diagnosis. The human microbiome is related to various respiratory diseases. However, the role of the lung microbiome in CIP and RP remains unknow [....] » Read More
Poster Presentation (In-Person)
Background: Since 2007, evidence supporting the role of physical activity (PA) in cancer prevention and survivorship has grown substantially. While early research focused on cancers such as colon, breast, and endometrial, more recent findings have consistently identified PA as a [....] » Read More
Poster Presentation (In-Person)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with poor prognosis, in which translation initiation factor EIF3A acts as an oncogene. Although EIF3A is recognized as an m?A reader, whether EIF3A itself undergoes m?A modification and its therapeutic rel [....] » Read More
Poster Presentation (In-Person)
Title: Targeting SIRT7-Mediated DNA damage repair as a novel strategy in pancreatic cancer
Background: Pancreatic cancer is a highly lethal malignancy characterized by poor prognosis and limited therapeutic options. Recent evidence suggests that Sirtuin 7 (SIRT7), a nucleolar NAD?-dependent deacetylase, plays an oncogenic role in multiple cancers; however, its precise [....] » Read More
Poster Presentation (In-Person)
Title: Functional integration of the ATP synthasome drives mitochondrial efficiency in breast carcinoma
Background: This study investigates the metabolic alterations associated with breast cancer progression and elucidates the underlying mechanisms. Adenine nucleotide translocase 2 (ANT2), a mitochondrial protein essential for cellular energy metabolism, facilitates the exchange of [....] » Read More
Poster Presentation (In-Person)
Title: Targeting oral squamous cell carcinoma with thienopyrimidines
Oral squamous cell carcinoma (OSCC) is among the most aggressive and lethal cancers of the head and neck, often diagnosed at an advanced stage and marked by treatment resistance. In search of selective anticancer agents, we evaluated a series of 2-substituted 4-amino-thieno[2,3-d [....] » Read More
Keynote Presentation (Virtual)
Current screening methods—radiological imaging, DNA-based tests, and pathological assessments—often fail to detect malignancies at early stages. Despite technological advances, gene-based diagnostics specifically designed for early cancer detection remain limited. To [....] » Read More
Keynote Presentation (Virtual)
Title: Targeted gene and drug delivery nanosystems to hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the major causes of cancer mortality worldwide, highlighting the urgent need for the development of new therapeutic approaches, such as those involving the combination of gene therapy and chemotherapy, that potentially present higher thera [....] » Read More
Keynote Presentation (Virtual)
Title: Cell viability assays under radiofrequency application modulated by nanomaterials
In this keynote talk, it will be explored the use of the Hill model to assess the Benchmark dose (BMD), the lethal dose 50 (LD50), the cooperativity (E) and the dissociation constant (K) while analyzing cell viability data using nanomaterials. The presentation is addressed to dis [....] » Read More
Keynote Presentation (Virtual)
Title: Information leakage: Types, remedies, and open problems
Information Leakage threatens and questions the use of machine learning model in real-life clinical applications. In effect, information leakage is similar to vulgar overfitting, yet rather more subtle and even when detected much harder to remove. Some recent research i [....] » Read More
Oral Presentation (Virtual)
Title: The magic of gratitude
While cancer treatment often focuses on the patient, the emotional toll on caregivers is a critical yet under-recognized dimension of cancer care. Family members—particularly spouses and adult children—frequently shoulder overwhelming responsibilities that lead to bur [....] » Read More
Oral Presentation (Virtual)
Title: Instant high-sensitivity non-invasive in-vivo diagnosis during biopsy
Today, doctors have to wait until the tumor grows large enough to become detectable. At this stage, it is often too late to cure. Biopsy, the gold standard in cancer diagnostics, cannot detect tumors in real-time, is often invasive, and frequently misses microscopic-size tumors. [....] » Read More
Oral Presentation (Virtual)
Title: Extracellular vesicle pathways as regulators of tumor-vascular interactions in glioblastoma
Glioblastoma (GBM), the most prevalent astrocytic brain tumour, remains incurable in spite of decades of research. Florid neovascularization, a morphological hallmark of GBM, is still poorly understood, as is the role of blood vessels in mediating the access of immune cells into [....] » Read More
Oral Presentation (Virtual)
Title: The power of trust through the eyes of a patient
One of the first things to be impacted when a patient receives a cancer diagnosis is Trust. Trust in their body, in the world as they see it and very quickly they need to learn to build trust in their clinicians and the proposed pathways to tackle one of the toughest experiences [....] » Read More
Oral Presentation (Virtual)
Title: Is cancer theory incomplete?
According to one physicist, major advances in science arise from two sources. The first is the introduction of new data and the second is the study of inconsistencies in established knowledge. Has cancer research missed the boat? Classically, experimental carcinogenesis is a comp [....] » Read More
Oral Presentation (Virtual)
Background: Oncological therapies are often decided individually on the basis of biological factors like age or general condition pas the most important factors. Age can influence the choice of therapy, especially in NSCLC, since there are broad options of different therapies ava [....] » Read More
Oral Presentation (Virtual)
Title: Innovative fiber solutions for cancer diagnostics
The latest innovative fiber solutions to be reviewed for the advanced biomedical applications in 0.3- 16µm range, including multispectral diagnostics to define tumor margins in oncology ex-vivo and in- vivo, plus tumor detection with IR-fiber and Raman endoscopy. [....] » Read More
Oral Presentation (Virtual)
Title: From sequence of tumor liberated protein (TLP) to potential targets for diagnosis and therapy
Over the past few decades, tremendous progress has been made in the understanding of how cancer evades the immune system, which in turn offers new ways to stop cancer immune evasion in favor of eliminating cancer cells. TLP complexes (proteins released from tumors) show antigenic [....] » Read More
Oral Presentation (Virtual)
Statement of the problem: The late adverse effects of pelvic radiotherapy concern 5 to 10% of patients, which could be life threatening. However, a clear medical consensus concerning the clinical management of such healthy tissue sequelae does not exist. Our group has demonstrate [....] » Read More
Oral Presentation (Virtual)
Title: The regulatory role of endothelial RhoA on tumor microenvironment
Your abstract should summarize the content of your presentation, including the background, methods, results, and conclusions. About 250-500 words. The endothelial barrier plays an active role in tumor growth, dissemination and metastasis. For metastasis, the transendothel [....] » Read More
Oral Presentation (Virtual)
Title: Association between lung cancer and prostate cancer, 3 studied cases, short literature review
Background: The association of lung cancer with prostate cancer is little studied. In the Medscape site we do not have any reference to this association. Material and method: We have collected data from 3 concrete cases regarding this association and we evaluated the [....] » Read More
Oral Presentation (Virtual)
Background The sphingosine kinase 1 (SphK1)/sphingosine-1-phosphate (S1P) axis has been widely studied in cancer research due to its role in modulating sphingolipid metabolism, which determines cell survival or death. Furthermore, SphK1 inhibitors prevent catabolism of ceram [....] » Read More
Oral Presentation (Virtual)
Title: Targeting telomerase for its advent in cancer therapeutics
Telomerase has emerged as an important primary target in anticancer therapy. It is a distinctive reverse transcriptase enzyme, which extends the length of telomere at the 3′ chromosomal end, and uses telomerase reverse transcriptase (TERT) and telomerase RNA templatecontain [....] » Read More
Oral Presentation (Virtual)
Triple-negative breast cancer (TNBC) is a particularly aggressive type of breast cancer, known for its lack of effective treatments and unfavorable prognosis. The G protein-coupled estrogen receptor (GPER), a novel estrogen receptor, is linked to increased malignancy in various c [....] » Read More
Oral Presentation (Virtual)
Title: A single-cell multi-omics study of head and neck cancer in multiple sites
Head and neck cancer (HNC) comprises a group of aggressive malignant tumors originating from the upper aerodigestive tract, including the oral cavity, pharynx, and larynx. It ranks as the seventh most common cancer worldwide, with a five-year overall survival rate of approximatel [....] » Read More
Oral Presentation (Virtual)
The folic acid (FA) receptor is frequently overexpressed in ovarian cancer cells, making it an attractive target for receptor-mediated drug delivery. Carbon dots (CDs), a class of fluorescent nanoparticles, offer strong potential as nanocarriers due to their biocompatibility, hig [....] » Read More
Oral Presentation (Virtual)
Title: Nanotechnology-mediated precision drug delivery strategies for breast cancer treatment
Despite the use of therapeutic modalities such as surgery, chemotherapy, and radiotherapy, breast cancer remains a potentially fatal condition for humans. The primary problems with these treatments are their low efficacy and the inevitable side effects they do to the surroun [....] » Read More
Poster Presentation (Virtual)
Title: Cardiac coherence: A new approach to oncology medicine
In the oncology clinic, the issue of anguish, stress and anxiety is a very important part of treatment. These affects can also condition the outcome of treatment, as well as patients' experiences of their disease. Cancer has specific psychological repercussions compared with [....] » Read More
Poster Presentation (Virtual)
Title: A new universal fever definition and the unscientific nature of the conservative fever definition
No medical textbook tells us what the purpose of fever is. Without knowing this, no one in the world can define, test, or treat fever. The current definition, testing, and treatment of fever, which is constructed without knowing what the purpose of fever is, has no scientific bas [....] » Read More
Poster Presentation (Virtual)
Numerous clinical studies have found that high expression of Vascular Endothelial Growth Factor (VEGF) is closely associated with poor prognosis in Colorectal Cancer (CRC), including high tumor recurrence rates and short survival periods. However, observational studies are prone [....] » Read More
Poster Presentation (Virtual)
Title: Rare bone metastasis of neuroendocrine tumors of unknown origin: A case report and literature review
Background: Neuroendocrine tumors (NETs) are rare neoplasms, accounting for approximately 0.5% of all tumors, and are characterized by their potential to metastasize to the liver, lymph nodes, and bones. Bone metastases from NETs are uncommon, and cases with unknown primary orig [....] » Read More
Poster Presentation (Virtual)
Background: Triple-negative breast cancer (TNBC) represents the most aggressive and therapeutically challenging subtype of breast carcinoma, characterized by immune evasion and rapid progression. While immunotherapy has shown promise, resistance remains a critical barrier. This s [....] » Read More
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